Shakespeare luncheon

I’m in DC today to attend a luncheon here at the Cosmos Club on Shakespeare. I have a particular interest in Elizabethan England because it was a time when the beginnings of The Enlightenment were superimposed upon a society that was still very much into believing in the power of witchcraft–an interesting time indeed, with echos that apply I suppose to our own times. In any case, my idea is that there were, at the time, two parallel versions of explaining human mind: one that recognized the brain as the seat of consciousness and the other that became dualism (as exemplified by Decartes). What is most interesting to me is that the version closer to our own current theories of mind arising from the activity of brains, came out of the folk-wisdom (I think)–the same place that witchcraft was still thriving. And the dualism view–the version that while still accepted by many, is not the neuroscience consensus….the dualism view arose out of The Enlightenment.

Society for Neuroscience Redux

Thirty thousand plus neuroscientists will be leaving Washington today to head home. My sense is that it was an extraordinarily successful meeting in that there was a lot of serious new science to report.

The photo was taken just outside the DC convention center yesterday as neuroscientists headed towards China Town and its many restaurants. For those readers who enjoy my various complaints about Blackboard, you’ll note its corporate headquarters (brown building to the left).

Today back at Krasnow we have an advisory board meeting that will take up the morning. The Board is a terrific group of distinguished individuals who have given enormously to the Institute over the years, both materially and in terms of collective wisdom.

For that we are very grateful. Over the next year, the Board will be entering a new phase, which I’ll put out as a teaser. I hope to write more about that soon.

In the meantime, we’re looking forward to a very busy remainder of the week, and a Thanksgiving holiday that’s not too far off.

Erin Shuman steals the SFN11 show today

With an absolutely spectacular talk about her work on local control of protein synthesis and degradation in neurons. More here.

I thought the most provocative idea she put forward was the notion of local control of protein synthesis in axons as well as dendrites…and that these local loci may be a lot more important than just governing plasticity.

It’s great to see neuroscience taking the next steps towards becoming a mature field.

Neurolaw #SFN11

Yesterday’s big show was the Neuroscience and the Law symposium. Here is a good summary. Most interesting work was Abigail Baird’s–she’s at Vassar College: teenagers apparently get themselves in trouble by too much engagement of their prefrontal cortex rather than trusting their gut (amygdala and insula). That’s completely counter-intuitive to me because I have always viewed the prefrontal cortex as pretty much the last part of the brain to “get wired up” during human development. Her thesis: too much analytic/executive engagement of prefrontal cortex leads to potentially flawed logical decisions (perhaps especially when we haven’t had a lot of experiences) and too much sensitivity to peer pressure.

Technologies and asking scientific questions

It’s very interesting to me that with each wave of new technological innovation there is a corresponding wave of deployment into scientific instrumentation. And that new wave of scientific instrumentation makes possible a whole slew of new zeroth order questions for investigators to ask.

The key is to recognize the new waves when they happen and then to figure out what basic new questions they allow us to ask at the laboratory bench.

What will be the next follow on to fMRI in functional brain imaging?

A tree is like a neuron–especially after the leaves come down…

The wind is really blowing hard today and the leaves are flying off the limbs. Looking out my office window I already see lots of bare limbs, which day by day, take on the look and feel of apical pyramidal cell dendrites–this is appropriate for SFN11 week here in DC.

I feel bad for the 40,000 neuroscientists who are streaming in to DC as I write these words, only to find that Metro is on a weekend schedule because of Veterans Day (20 minutes between trains). Hope they all brought coats. It’s cold.

Some suggestions for our students, for whom this may well be their first meeting:

Concentrate on the poster sessions and focus with laser attention on the subset in your own area of work. This task alone, will, if done properly, take up the bulk of your working time at the meeting.

Tag along with your mentor, as much as she or he, will allow and observe how networking happens. If you’re lucky, you may end up being introduced to your next boss!

When socializing, especially early in the evening, don’t party too hearty. You don’t want to wake up to your picture on Facebook. And you don’t want to fall into your soup.

Time Running out for the Super Committee

The effects on science and technology funding here in the States could be devastating. Here is the latest from Science Magazine.

My own take is that the Committee will, in fact, probably fail. But the mandatory cuts wont go into effect until Fiscal Year 2013, after the general election. With a new Congress and potentially a new Administration, the law certainly can be rewritten and probably would be.

The central point here is that science funding falls into the category known as discretionary (I know, Beltway-ese). Cuts in discretionary funding wont really do anything substantive to the budget deficit issues. For cuts to be meaningful, as far as the national debt and the deficit, they would need to be in the category called mandatory. Medicare and Medicaid are in this category–and health care is the elephant in the room.