Evan Frick’s paper in this week’s science, here. What’s really interesting to me is not so much the result (which isn’t really surprising: that terrestrial mammal food webs have been collapsing) but the use of AI to address the complexity of how the ‘phenotype’ of the biosphere changes over time.
Center for Biomedical Science and Policy
Our newly minted center at George Mason’s Schar School, here. With my co-director, Naoru Koizumi, we are building a new nexus between the clinic, the bench and policy makers.
One of my favorite places….
Fogo Island, here. Atlantic Canada is under-appreciated.
Terraforming Mars for less…
Loyal readers know that I am fascinated with the red planet. Hat tip to Tyler on this blogpost from Casey Handmer. Casey worked at Hyperloop and NASA’s Jet Propulsion Laboratory before founding his own company. A Caltech PhD, he knows his stuff.
Open-access on steroids…
The story from SCIENCE, is here. The upshot is that journal articles that result from US-funded research have to be made available for free to the public as soon as published. No more year-long paywall. The idea, is that the taxpayer already paid for the work once and that having to pay again for access is double-billing. Apparently this also goes for the data. I’m for this, but how this will actually be implemented isn’t clear. Someone has to pay for the editorial labor. Will the publishing fees now be written into a grant proposal budget as allowable direct costs? A lot of business models are going to have to change I think.
One caveat: all of this is reversible by a successor Administration.
Known unknowns
- What happens at the singularity in a Black Hole
- Why the parameterization of the universe (e.g. Planck’s constant) seem tuned for us to exist
- What in the brain explains the ‘hard problem’ of consciousness
- Why plant phospholipid metabolism is so different from animals or yeast
- The proto-function of the ribosome before proteins came on the scene
- Before the Big Bang
- Fermi’s paradox
- When will the next pandemic hit
- Will humans persist into the 22nd century
When AI’s become PI’s…
It is being deployed across the entire waterfront of science from particle physics to ecology. We use it to replace routine human labor, adapt models, direct autonomous vehicles and to reconfigure sensors in response to interesting events. There is still a human in the loop, but one can see the not so distant future where the artifact will be creating the hypothesis and testing it experimentally.
From the performance of the most recent Large Language Models, it’s not such a far jump to imagine accurate Wikipedia entries by AI authors–although, there is always the alignment problem: what is to stop the AI from producing realistic-looking drivel, either accidentally or to fool us.
Jane Silverthorne RIP
Sad to report the passing of my former deputy at NSF, Dr. Jane Silverthorne, a superb plant biologist.
Job Searching in Academia for Post Docs: Part III
As part of your short-list visit to campus, you can expect to be hosted for dinner usually at a nice restaurant (although it could be at a faculty member’s house). This will come at the end of what has already been a long day. Don’t relax. This dinner will be all work and no play. From a practical standpoint, it would be good if you have time to clean up a bit after your long day. If you brought something else to wear that is appropriate to the occasion, then changing into those clothes would be helpful. If you order, try to order food for which there is no chance of it spilling on to you or others (red Italian sauces should be off the list). Aim for a price point that is in the middle of the menu and that doesn’t stand out. If you have special dietary needs, those should he communicated to the host before you travel. You may be offered an adult beverage (i.e. alcohol) either before or during dinner. Politely decline it. The offer is, among other things, a test of your judgement for which there is only one correct answer. You will need to be completely sober during the dinner. Note that the other attendees may well imbibe a bit.
The dinner will be a continuation of the interview process. It may masquerade as convivial conversation, but it is not. Each opportunity for you to converse will be analyzed by the attendees for the key factors of: intelligence, fitting in and good judgement. All of these are considered to be necessary for the success in the search. Do not discuss politics or volunteer your political opinions. Do not monopolize the conversation. Try to actively listen to each person as they speak. Make eye contact with the other attendees as they are speaking. Often, it’s a good idea to feed their question back to them as a question in order to buy time to think and to make certain that you both are on the same page.
At the end of the evening, make certain to explicitly thank the host and the other attendees for their time and hospitality. And you aren’t off camera until you are back in your hotel room with the door closed. Don’t even think about going out afterwards.
Job Searching in Academia for Postdocs Part II
So you’ve been invited to visit a campus as part of your job search. By definition, you’ve made the ‘short list’. Congrats. To prepare for your visit, you’ll need to have the following in your back pocket (meaning ‘in the can’): a job talk, an informal whiteboard talk, and the ability to actively listen to many different interviewer-stakeholders for a period extending beyond the workday going well into the evening. There is no room for messing up on any of these because the competition is extensive.
The job talk speaks for itself and a lot has been written about the subject. So, I’ll just add my own emphasis on never reading from your slides, keeping bulleted text to a minimum and ending the talk at the 45-50 minute mark to leave just the right amount of time for questions. I’d also remind readers to always cite the use of other’s graphics and to concentrate the talk on your own new data.
Less has been written about the informal whiteboard talk. In fact, a lot of candidates aren’t aware of its ubiquitous existence (in one form or another). This is the talk where you lay out (in outline form) the substance of your first grant proposal for sponsored research funding. First, all money is not equivalent. If you are in the natural or social sciences (including biomedical), I’d highly recommend that you lay out a proposal to either the NSF or the NIH. Your potential future colleagues will tend to view funding from those agencies as more prestigious and worthy than funding from other sources. Do I agree with that take? Definitely not, but that’s the current state of the academy so you should be aware. If you are going to outline an NSF proposal, that make a clear distinction between the Intellectual Merit and Broader Impacts criteria. If you are outlining an NIH proposal, then organize the whiteboard talk as modular specific aims that, taken together, form a coherent flow chart. The key is that the ideas are novel, they align with the interests of the hiring department, and most importantly that your track record supports the likely success of the proposal.
Who will be your audience for this whiteboard presentation? It might be just the department chair or dean. Or it might be the entire search committee. In any case, this part of your day’s work is critical.
Next up we’ll cover stakeholder interviews and the dinner out.